The Arab American University is distinguished by having two campuses.

The first is the main campus in Jenin, which serves as the university's core and attracts thousands of students from all over Palestine. It is known for its large area, diverse academic programs that include scientific, technical, and humanities disciplines, as well as its modern facilities that support education and research.

The second campus in Ramallah was established to meet the needs of students in the central West Bank. The University offers a range of master's, doctoral, and higher diploma programs. Several bachelor's and diploma programs have also been introduced, aligned with the University's focus on technological development, digital transformation, as well as the needs of the labor market. The campus enjoys a strategic location and is easily accessible, providing students with a modern and dynamic educational environment that fosters creativity and excellence.

Having two campuses reflects the University's commitment to providing distinguished education that meets the needs of students at all levels and across different regions.