Thesis\Treatise Track: Total Credit Hours Required to Finish the Degree ( 36 Credit Hours ) as Follows
Specialization Requirements
Students must pass all of the following courses plus ( 6 ) credit hours for the Thesis
|
Course Number |
Course Name |
Weekly Hours |
Cr. Hrs. |
Prerequisite |
||
|---|---|---|---|---|---|---|
|
Theoretical |
Practical |
|||||
| 151056000 | ADVANCED RESEARCH METHODS | The course provides a theoretical and practical introduction to basic and advanced laboratory techniques in biomedical sciences, such as PCR, Microarray analysis, DNA sequencing basic and second generation (exome sequencing), blotting techniques, FISH, HPLC, Density gradient fractionation, Cell culture, and other techniques. | 3 | - | 3 |
- |
| 151056050 | ADVANCED BIOCHEMISTRY | This course will cover a basic yet solid understanding of metabolism, enzymology mechanisms and kinetics, as well as theoretical aspects of various laboratory techniques. In addition, an introduction to modern biochemical techniques, including analytical methods for macromolecules, enzyme reactions, spectrophotometry, and purification of proteins, centrifugation, chromatography, electrophoresis, pH and ion specific electrodes, radioisotope tracer methodology will be introduced. | 3 | - | 3 |
- |
| 151056070 | ADVANCED CELL BIOLOGY | This course includes detailed description and discussion on the molecular structure and function of various cell components, their significance in cell survival and differentiation. Cell division and the cell cycle control will be discussed in details at the molecular level. Cell membranes and cytoskeleton components including microtubules, intermediate filaments and microfilaments structure and role in cell survival will be thoroughly discussed. The course will also include detailed discussion on critical processes that are essential for cell survival including cell signaling mechanisms, cell-cell interaction, cell differentiation and apoptosis | 3 | - | 3 |
- |
| 151056090 | ADVANCED MOLECULAR BIOLOGY | This course covers protein and nucleic acid structure, DNA metabolism, gene expression, gene regulation, genomics and bioinformatics. The course will emphasize readings from the current literature. | 3 | - | 3 |
- |
| 151056110 | GENE REGULATION MECHANISMS | The course will deal with the various levels of controlling gene activity at different levels including transcriptional, posttranscriptional and epigenetic control. This will include thorough discussions in prokaryotic and eukaryotic systems. The experimental approaches used in gene regulation investigations including in vitro and in vivo systems will constitute a primary objective of the course. The role of genes in developmental biology will also be discussed in the drosophila model and other related model systems. | 3 | - | 3 |
- |
| 151056130 | BIOINFORMATICS | The course will provide student with the major concepts and methods of bioinformatics. Topics include, but not limited to, statistics & probability theory, alignments genetics, phylogenetics, genomics, data mining, protein structure, cell simulation and computing. | 2 | - | 2 |
- |
| 151056150 | SEMINAR | This course will train students on how to choose a recent research topic of interest for presentation, preparation and clarity of the presented material, presentation strategies, objective discussion and criticism, overall concluding remarks and final take home summary of the presented material. The course will include model presentations by the faculty and students will be asked to prepare two presentations during the semester. | 1 | - | 1 |
- |
Students must pass ( 12 ) credit hours from any of the following courses
|
Course Number |
Course Name |
Weekly Hours |
Cr. Hrs. |
Prerequisite |
||
|---|---|---|---|---|---|---|
|
Theoretical |
Practical |
|||||
| 151056170 | MOLECULAR EPIDEMIOLOGY | This course will cover designs and methods for genetic epidemiology studies. Several population genetics concepts relevant to understanding genetic epidemiology designs and statistical tools will be introduced including concepts of quantitative and qualitative traits, genetic risk models, migration and admixture, inbreeding and allele/haplotype frequency estimation. Interaction assessment will also be presented Research methods for evaluating genetic influences on disease and risk factors and genetic-environmental interactions. Study designs and statistical methods include twin studies, family studies, population-based association studies, segregation analysis, and linkage analysis population will be discussed. | 3 | - | 3 |
151056090 ADVANCED MOLECULAR BIOLOGY This course covers protein and nucleic acid structure, DNA metabolism, gene expression, gene regulation, genomics and bioinformatics. The course will emphasize readings from the current literature. |
| 151056190 | GENETIC TOXICOLOGY | Prerequisite: Advanced Biochemistry. Analyzes the modes by which organisms handle damage to DNA by physical and chemical agents, the mechanisms of converting damage to mutations, and the theoretical basis for carcinogenesis screening methods utilizing mutagenesis. Topics include systems for mutagenesis testing, mutational spectra, and inducible responses to DNA damage. | 3 | - | 3 |
151056050 ADVANCED BIOCHEMISTRY This course will cover a basic yet solid understanding of metabolism, enzymology mechanisms and kinetics, as well as theoretical aspects of various laboratory techniques. In addition, an introduction to modern biochemical techniques, including analytical methods for macromolecules, enzyme reactions, spectrophotometry, and purification of proteins, centrifugation, chromatography, electrophoresis, pH and ion specific electrodes, radioisotope tracer methodology will be introduced. |
| 151056210 | CYTOGENETICS | This course will covere the current concepts of genetics with concentration on human genetics; it will provide information regarding etiology, molecular features, testing and treatment of a variety of human genetic disorders. It will cover advanced knowledge of the molecular mutagenesis. It will also provide the theory and hands-on experience of laboratory techniques currently used in diagnostic cytogenetics. The student will acquire the skills and techniques required to process blood, amniotic fluid and solid tissue specimens from receipt to chromosome analysis. It will also address some advanced genetic issues such as mitochondrial disorders, microdeletions and duplications and methylation. | 3 | - | 3 |
151056070 ADVANCED CELL BIOLOGY This course includes detailed description and discussion on the molecular structure and function of various cell components, their significance in cell survival and differentiation. Cell division and the cell cycle control will be discussed in details at the molecular level. Cell membranes and cytoskeleton components including microtubules, intermediate filaments and microfilaments structure and role in cell survival will be thoroughly discussed. The course will also include detailed discussion on critical processes that are essential for cell survival including cell signaling mechanisms, cell-cell interaction, cell differentiation and apoptosis |
| 151056230 | PROTEOMICS | The Proteomics course will cover fundamentals of mass spectrometry and proteomics, essential “bottom up” protein identification, quantitative and high throughput proteomics, posttranslational modifications, “top down” proteomics, imaging mass spectrometry, mass spectrometry for structural biology, specialty mass spectrometry applications, data analysis, and bioinformatics. There will be assignments emphasizing data analysis, both fundamental and advanced, throughout the course. Readings from the literature will be assigned throughout the course. Individual or small group sessions will be carried out in the laboratory. The course emphasizes the link between mass spectrometry and biological insights. | 2 | - | 2 |
151056090 ADVANCED MOLECULAR BIOLOGY This course covers protein and nucleic acid structure, DNA metabolism, gene expression, gene regulation, genomics and bioinformatics. The course will emphasize readings from the current literature. |
| 151056250 | BIOCHEMICAL TOXICOLOGY | This course includes fundamental understanding of biochemical, molecular and cellular mechanisms, through which xenobiotics alter cellular homeostasis, produce toxicity and alter organ function. Additonally, it has the concepts behind the current biochemical, molecular and cellular experimental approaches for study of biochemical mechanisms of toxicity. | 3 | - | 3 |
151056050 ADVANCED BIOCHEMISTRY This course will cover a basic yet solid understanding of metabolism, enzymology mechanisms and kinetics, as well as theoretical aspects of various laboratory techniques. In addition, an introduction to modern biochemical techniques, including analytical methods for macromolecules, enzyme reactions, spectrophotometry, and purification of proteins, centrifugation, chromatography, electrophoresis, pH and ion specific electrodes, radioisotope tracer methodology will be introduced. |
| 151056270 | ANTIOXIDANTS AND FREE RADICALS | The course describes the significance of oxygen and nitrogen derivatives in the human body in normal physiological processes and in cases of pathologies; characterization of antioxidants and their presence in the organism. Particular diseases, the origin and/or the course of which are closely connected with free radicals or active oxygen and nitrogen forms, will be examined during the course. The students will learn about antioxidants in food and beverages and about the efficiency of antioxidative food additives and microelements, and the necessity to control the use of antioxidants. The students will learn how to determine metabolites of lipid peroxidation processes and antioxidative enzymes and microelements in the blood. | 3 | - | 3 |
151056050 ADVANCED BIOCHEMISTRY This course will cover a basic yet solid understanding of metabolism, enzymology mechanisms and kinetics, as well as theoretical aspects of various laboratory techniques. In addition, an introduction to modern biochemical techniques, including analytical methods for macromolecules, enzyme reactions, spectrophotometry, and purification of proteins, centrifugation, chromatography, electrophoresis, pH and ion specific electrodes, radioisotope tracer methodology will be introduced. |
| 151056310 | APOPTOSIS | The course will cover the various topics in apoptosis, Introduction to programmed cell death and apoptosis, the BCL-2 family of proteins, Apaf proteins, Caspases, Mechanisms that regulate apoptosis, Non-apoptotic functions of components of the central apoptosis machinery, Diseases caused by deregulated apoptosis | 2 | - | 2 |
151056090 ADVANCED MOLECULAR BIOLOGY This course covers protein and nucleic acid structure, DNA metabolism, gene expression, gene regulation, genomics and bioinformatics. The course will emphasize readings from the current literature. |
| 151056330 | MOLECULAR BASIS OF DISEASES | This course will cover the pathology of selected human diseasese at the molecular level including inborn errors of metabolism, hemoglobinopathies, bleeding disorders and structural protein abnormalities and neurogenetics. Diverse advesr celluar changes that are part of the disease mechanism saddress including toxic damage to cells, repair processes within cells, cell aging and mechanisms of cell death will beb discussed. The molecular and cellular changes that lead to diverse clinical features in inherited syndromes, cancer, multifactorial diseases, the role of trace elements in human biology and disease will also be addressed. | 3 | - | 3 |
151056050 ADVANCED BIOCHEMISTRY This course will cover a basic yet solid understanding of metabolism, enzymology mechanisms and kinetics, as well as theoretical aspects of various laboratory techniques. In addition, an introduction to modern biochemical techniques, including analytical methods for macromolecules, enzyme reactions, spectrophotometry, and purification of proteins, centrifugation, chromatography, electrophoresis, pH and ion specific electrodes, radioisotope tracer methodology will be introduced. 151056090 ADVANCED MOLECULAR BIOLOGY This course covers protein and nucleic acid structure, DNA metabolism, gene expression, gene regulation, genomics and bioinformatics. The course will emphasize readings from the current literature. |
| 151056350 | PHARMACOGENOMICS | This course involves thorough discussion on understanding the modern approach to elucidate the spectrum of single nucleotide polymorphisms (SNPs) and mutations in specific target genes in correlation with the efficacy of drug therapy to treat serious diseases. The strategy of linking specific target genes to a particular disease will be discussed including direct approach, second generation sequencing, genome wide association (GWA) and other approaches. Current successful investigations and applications to serious diseases including thrombophelia, leukemias and Lymphomas will be utilized as model systems to illustrate the potential of using genetics to develop patients' oriented therapy in order to optimize drug response and minimize treatment duration. | 3 | - | 3 |
151056050 ADVANCED BIOCHEMISTRY This course will cover a basic yet solid understanding of metabolism, enzymology mechanisms and kinetics, as well as theoretical aspects of various laboratory techniques. In addition, an introduction to modern biochemical techniques, including analytical methods for macromolecules, enzyme reactions, spectrophotometry, and purification of proteins, centrifugation, chromatography, electrophoresis, pH and ion specific electrodes, radioisotope tracer methodology will be introduced. 151056090 ADVANCED MOLECULAR BIOLOGY This course covers protein and nucleic acid structure, DNA metabolism, gene expression, gene regulation, genomics and bioinformatics. The course will emphasize readings from the current literature. |
| 151056370 | GENETIC ENGINEERING | This course covers the definitions and applications of biotechnology and genetic engineering; it surveys the latest applications of recombinant DNA technology in medical diagnosis and therapy, microbial biotechnology and environmental biotechnology. Lectures will underlie the principles and applications of recombinant DNA technology. | 2 | - | 2 |
151056090 ADVANCED MOLECULAR BIOLOGY This course covers protein and nucleic acid structure, DNA metabolism, gene expression, gene regulation, genomics and bioinformatics. The course will emphasize readings from the current literature. |
| 151056380 | CANCER GENETICS | 3 | - | 3 |
151056070 ADVANCED CELL BIOLOGY This course includes detailed description and discussion on the molecular structure and function of various cell components, their significance in cell survival and differentiation. Cell division and the cell cycle control will be discussed in details at the molecular level. Cell membranes and cytoskeleton components including microtubules, intermediate filaments and microfilaments structure and role in cell survival will be thoroughly discussed. The course will also include detailed discussion on critical processes that are essential for cell survival including cell signaling mechanisms, cell-cell interaction, cell differentiation and apoptosis |
|
| 151056390 | SPECIAL TOPICS | In this course, students will be exposed in details to recent studies and research interest in a specific topic of high significance in one of the main focuses of the program. The discussion will include learning about the model systems used in the investigations, study design, main findings and discoveries and their potential applications. In addition, the course may include teaching a specific topic relevant to the program upon the availability of a specialist who will enrich student's knowledge and broaden their scope of interest in that field. | 1 | - | 1 |
- |
| 151056550 | GENE THERAPY | The course will discuss the modenrn approaches used in treating genetic diseases by introducing a normal functional gene in specific target cells or programing stem cells to copensate for the defective gene causing the clinical defect. The approach of using various vectors and other transfer stratigies to transfer the specific gene using specific models with their relative specificity, efficiency with their potential interference with the normal funcion of target cells will be thoroughly discussed with main focus on their potential mutagenesis and cell transformation effect. In addition, the various approaches used to suppress specific genes using interfering molecules or introduction of toxic genes to control cell transformation will also be discussed in details. The potential current and future stratigies used to repair defective genes by targeted recombination will also be introduced and discussed. | 2 | - | 2 |
151056090 ADVANCED MOLECULAR BIOLOGY This course covers protein and nucleic acid structure, DNA metabolism, gene expression, gene regulation, genomics and bioinformatics. The course will emphasize readings from the current literature. |
| 151056650 | LAB TECHNIQUES | This course will focus on enriching students’ practical research skills and developing their ability in designing research and experiments to answer a specific biological question. They will get introduced to different techniques used in the field of molecular genetics including mutagenesis primer design and mutagenesis PCR, Bacterial transformation and selection for colonies expressing mutated plasmid, plasmid sequencing, RFLP and ARMS, Cell transfection and infection, RNA extraction, cDNA synthesis and Real time PCR , Protein isolation and western blots, | 3 | - | 3 |
- |
| 151056700 | IMMUNOGENETICS | 3 | - | 3 |
- |
|
Comprehensive Exam Track: Total Credit Hours Required to Finish the Degree ( 36 Credit Hours ) as Follows
Specialization Requirements
Students must pass all of the following courses
|
Course Number |
Course Name |
Weekly Hours |
Cr. Hrs. |
Prerequisite |
||
|---|---|---|---|---|---|---|
|
Theoretical |
Practical |
|||||
| 151056000 | ADVANCED RESEARCH METHODS | The course provides a theoretical and practical introduction to basic and advanced laboratory techniques in biomedical sciences, such as PCR, Microarray analysis, DNA sequencing basic and second generation (exome sequencing), blotting techniques, FISH, HPLC, Density gradient fractionation, Cell culture, and other techniques. | 3 | - | 3 |
- |
| 151056050 | ADVANCED BIOCHEMISTRY | This course will cover a basic yet solid understanding of metabolism, enzymology mechanisms and kinetics, as well as theoretical aspects of various laboratory techniques. In addition, an introduction to modern biochemical techniques, including analytical methods for macromolecules, enzyme reactions, spectrophotometry, and purification of proteins, centrifugation, chromatography, electrophoresis, pH and ion specific electrodes, radioisotope tracer methodology will be introduced. | 3 | - | 3 |
- |
| 151056070 | ADVANCED CELL BIOLOGY | This course includes detailed description and discussion on the molecular structure and function of various cell components, their significance in cell survival and differentiation. Cell division and the cell cycle control will be discussed in details at the molecular level. Cell membranes and cytoskeleton components including microtubules, intermediate filaments and microfilaments structure and role in cell survival will be thoroughly discussed. The course will also include detailed discussion on critical processes that are essential for cell survival including cell signaling mechanisms, cell-cell interaction, cell differentiation and apoptosis | 3 | - | 3 |
- |
| 151056090 | ADVANCED MOLECULAR BIOLOGY | This course covers protein and nucleic acid structure, DNA metabolism, gene expression, gene regulation, genomics and bioinformatics. The course will emphasize readings from the current literature. | 3 | - | 3 |
- |
| 151056110 | GENE REGULATION MECHANISMS | The course will deal with the various levels of controlling gene activity at different levels including transcriptional, posttranscriptional and epigenetic control. This will include thorough discussions in prokaryotic and eukaryotic systems. The experimental approaches used in gene regulation investigations including in vitro and in vivo systems will constitute a primary objective of the course. The role of genes in developmental biology will also be discussed in the drosophila model and other related model systems. | 3 | - | 3 |
- |
| 151056130 | BIOINFORMATICS | The course will provide student with the major concepts and methods of bioinformatics. Topics include, but not limited to, statistics & probability theory, alignments genetics, phylogenetics, genomics, data mining, protein structure, cell simulation and computing. | 2 | - | 2 |
- |
| 151056150 | SEMINAR | This course will train students on how to choose a recent research topic of interest for presentation, preparation and clarity of the presented material, presentation strategies, objective discussion and criticism, overall concluding remarks and final take home summary of the presented material. The course will include model presentations by the faculty and students will be asked to prepare two presentations during the semester. | 1 | - | 1 |
- |
| 151056750 | SEMINAR I | 3 | - | 3 |
- |
|
| 151056800 | SEMINAR II | 3 | - | 3 |
- |
|
Students must pass ( 12 ) credit hours from any of the following courses
|
Course Number |
Course Name |
Weekly Hours |
Cr. Hrs. |
Prerequisite |
||
|---|---|---|---|---|---|---|
|
Theoretical |
Practical |
|||||
| 151056170 | MOLECULAR EPIDEMIOLOGY | This course will cover designs and methods for genetic epidemiology studies. Several population genetics concepts relevant to understanding genetic epidemiology designs and statistical tools will be introduced including concepts of quantitative and qualitative traits, genetic risk models, migration and admixture, inbreeding and allele/haplotype frequency estimation. Interaction assessment will also be presented Research methods for evaluating genetic influences on disease and risk factors and genetic-environmental interactions. Study designs and statistical methods include twin studies, family studies, population-based association studies, segregation analysis, and linkage analysis population will be discussed. | 3 | - | 3 |
151056090 ADVANCED MOLECULAR BIOLOGY This course covers protein and nucleic acid structure, DNA metabolism, gene expression, gene regulation, genomics and bioinformatics. The course will emphasize readings from the current literature. |
| 151056190 | GENETIC TOXICOLOGY | Prerequisite: Advanced Biochemistry. Analyzes the modes by which organisms handle damage to DNA by physical and chemical agents, the mechanisms of converting damage to mutations, and the theoretical basis for carcinogenesis screening methods utilizing mutagenesis. Topics include systems for mutagenesis testing, mutational spectra, and inducible responses to DNA damage. | 3 | - | 3 |
151056050 ADVANCED BIOCHEMISTRY This course will cover a basic yet solid understanding of metabolism, enzymology mechanisms and kinetics, as well as theoretical aspects of various laboratory techniques. In addition, an introduction to modern biochemical techniques, including analytical methods for macromolecules, enzyme reactions, spectrophotometry, and purification of proteins, centrifugation, chromatography, electrophoresis, pH and ion specific electrodes, radioisotope tracer methodology will be introduced. |
| 151056210 | CYTOGENETICS | This course will covere the current concepts of genetics with concentration on human genetics; it will provide information regarding etiology, molecular features, testing and treatment of a variety of human genetic disorders. It will cover advanced knowledge of the molecular mutagenesis. It will also provide the theory and hands-on experience of laboratory techniques currently used in diagnostic cytogenetics. The student will acquire the skills and techniques required to process blood, amniotic fluid and solid tissue specimens from receipt to chromosome analysis. It will also address some advanced genetic issues such as mitochondrial disorders, microdeletions and duplications and methylation. | 3 | - | 3 |
151056070 ADVANCED CELL BIOLOGY This course includes detailed description and discussion on the molecular structure and function of various cell components, their significance in cell survival and differentiation. Cell division and the cell cycle control will be discussed in details at the molecular level. Cell membranes and cytoskeleton components including microtubules, intermediate filaments and microfilaments structure and role in cell survival will be thoroughly discussed. The course will also include detailed discussion on critical processes that are essential for cell survival including cell signaling mechanisms, cell-cell interaction, cell differentiation and apoptosis |
| 151056230 | PROTEOMICS | The Proteomics course will cover fundamentals of mass spectrometry and proteomics, essential “bottom up” protein identification, quantitative and high throughput proteomics, posttranslational modifications, “top down” proteomics, imaging mass spectrometry, mass spectrometry for structural biology, specialty mass spectrometry applications, data analysis, and bioinformatics. There will be assignments emphasizing data analysis, both fundamental and advanced, throughout the course. Readings from the literature will be assigned throughout the course. Individual or small group sessions will be carried out in the laboratory. The course emphasizes the link between mass spectrometry and biological insights. | 2 | - | 2 |
151056090 ADVANCED MOLECULAR BIOLOGY This course covers protein and nucleic acid structure, DNA metabolism, gene expression, gene regulation, genomics and bioinformatics. The course will emphasize readings from the current literature. |
| 151056250 | BIOCHEMICAL TOXICOLOGY | This course includes fundamental understanding of biochemical, molecular and cellular mechanisms, through which xenobiotics alter cellular homeostasis, produce toxicity and alter organ function. Additonally, it has the concepts behind the current biochemical, molecular and cellular experimental approaches for study of biochemical mechanisms of toxicity. | 3 | - | 3 |
151056050 ADVANCED BIOCHEMISTRY This course will cover a basic yet solid understanding of metabolism, enzymology mechanisms and kinetics, as well as theoretical aspects of various laboratory techniques. In addition, an introduction to modern biochemical techniques, including analytical methods for macromolecules, enzyme reactions, spectrophotometry, and purification of proteins, centrifugation, chromatography, electrophoresis, pH and ion specific electrodes, radioisotope tracer methodology will be introduced. |
| 151056270 | ANTIOXIDANTS AND FREE RADICALS | The course describes the significance of oxygen and nitrogen derivatives in the human body in normal physiological processes and in cases of pathologies; characterization of antioxidants and their presence in the organism. Particular diseases, the origin and/or the course of which are closely connected with free radicals or active oxygen and nitrogen forms, will be examined during the course. The students will learn about antioxidants in food and beverages and about the efficiency of antioxidative food additives and microelements, and the necessity to control the use of antioxidants. The students will learn how to determine metabolites of lipid peroxidation processes and antioxidative enzymes and microelements in the blood. | 3 | - | 3 |
151056050 ADVANCED BIOCHEMISTRY This course will cover a basic yet solid understanding of metabolism, enzymology mechanisms and kinetics, as well as theoretical aspects of various laboratory techniques. In addition, an introduction to modern biochemical techniques, including analytical methods for macromolecules, enzyme reactions, spectrophotometry, and purification of proteins, centrifugation, chromatography, electrophoresis, pH and ion specific electrodes, radioisotope tracer methodology will be introduced. |
| 151056310 | APOPTOSIS | The course will cover the various topics in apoptosis, Introduction to programmed cell death and apoptosis, the BCL-2 family of proteins, Apaf proteins, Caspases, Mechanisms that regulate apoptosis, Non-apoptotic functions of components of the central apoptosis machinery, Diseases caused by deregulated apoptosis | 2 | - | 2 |
151056090 ADVANCED MOLECULAR BIOLOGY This course covers protein and nucleic acid structure, DNA metabolism, gene expression, gene regulation, genomics and bioinformatics. The course will emphasize readings from the current literature. |
| 151056330 | MOLECULAR BASIS OF DISEASES | This course will cover the pathology of selected human diseasese at the molecular level including inborn errors of metabolism, hemoglobinopathies, bleeding disorders and structural protein abnormalities and neurogenetics. Diverse advesr celluar changes that are part of the disease mechanism saddress including toxic damage to cells, repair processes within cells, cell aging and mechanisms of cell death will beb discussed. The molecular and cellular changes that lead to diverse clinical features in inherited syndromes, cancer, multifactorial diseases, the role of trace elements in human biology and disease will also be addressed. | 3 | - | 3 |
151056050 ADVANCED BIOCHEMISTRY This course will cover a basic yet solid understanding of metabolism, enzymology mechanisms and kinetics, as well as theoretical aspects of various laboratory techniques. In addition, an introduction to modern biochemical techniques, including analytical methods for macromolecules, enzyme reactions, spectrophotometry, and purification of proteins, centrifugation, chromatography, electrophoresis, pH and ion specific electrodes, radioisotope tracer methodology will be introduced. 151056090 ADVANCED MOLECULAR BIOLOGY This course covers protein and nucleic acid structure, DNA metabolism, gene expression, gene regulation, genomics and bioinformatics. The course will emphasize readings from the current literature. |
| 151056350 | PHARMACOGENOMICS | This course involves thorough discussion on understanding the modern approach to elucidate the spectrum of single nucleotide polymorphisms (SNPs) and mutations in specific target genes in correlation with the efficacy of drug therapy to treat serious diseases. The strategy of linking specific target genes to a particular disease will be discussed including direct approach, second generation sequencing, genome wide association (GWA) and other approaches. Current successful investigations and applications to serious diseases including thrombophelia, leukemias and Lymphomas will be utilized as model systems to illustrate the potential of using genetics to develop patients' oriented therapy in order to optimize drug response and minimize treatment duration. | 3 | - | 3 |
151056050 ADVANCED BIOCHEMISTRY This course will cover a basic yet solid understanding of metabolism, enzymology mechanisms and kinetics, as well as theoretical aspects of various laboratory techniques. In addition, an introduction to modern biochemical techniques, including analytical methods for macromolecules, enzyme reactions, spectrophotometry, and purification of proteins, centrifugation, chromatography, electrophoresis, pH and ion specific electrodes, radioisotope tracer methodology will be introduced. 151056090 ADVANCED MOLECULAR BIOLOGY This course covers protein and nucleic acid structure, DNA metabolism, gene expression, gene regulation, genomics and bioinformatics. The course will emphasize readings from the current literature. |
| 151056370 | GENETIC ENGINEERING | This course covers the definitions and applications of biotechnology and genetic engineering; it surveys the latest applications of recombinant DNA technology in medical diagnosis and therapy, microbial biotechnology and environmental biotechnology. Lectures will underlie the principles and applications of recombinant DNA technology. | 2 | - | 2 |
151056090 ADVANCED MOLECULAR BIOLOGY This course covers protein and nucleic acid structure, DNA metabolism, gene expression, gene regulation, genomics and bioinformatics. The course will emphasize readings from the current literature. |
| 151056380 | CANCER GENETICS | 3 | - | 3 |
151056070 ADVANCED CELL BIOLOGY This course includes detailed description and discussion on the molecular structure and function of various cell components, their significance in cell survival and differentiation. Cell division and the cell cycle control will be discussed in details at the molecular level. Cell membranes and cytoskeleton components including microtubules, intermediate filaments and microfilaments structure and role in cell survival will be thoroughly discussed. The course will also include detailed discussion on critical processes that are essential for cell survival including cell signaling mechanisms, cell-cell interaction, cell differentiation and apoptosis |
|
| 151056390 | SPECIAL TOPICS | In this course, students will be exposed in details to recent studies and research interest in a specific topic of high significance in one of the main focuses of the program. The discussion will include learning about the model systems used in the investigations, study design, main findings and discoveries and their potential applications. In addition, the course may include teaching a specific topic relevant to the program upon the availability of a specialist who will enrich student's knowledge and broaden their scope of interest in that field. | 1 | - | 1 |
- |
| 151056550 | GENE THERAPY | The course will discuss the modenrn approaches used in treating genetic diseases by introducing a normal functional gene in specific target cells or programing stem cells to copensate for the defective gene causing the clinical defect. The approach of using various vectors and other transfer stratigies to transfer the specific gene using specific models with their relative specificity, efficiency with their potential interference with the normal funcion of target cells will be thoroughly discussed with main focus on their potential mutagenesis and cell transformation effect. In addition, the various approaches used to suppress specific genes using interfering molecules or introduction of toxic genes to control cell transformation will also be discussed in details. The potential current and future stratigies used to repair defective genes by targeted recombination will also be introduced and discussed. | 2 | - | 2 |
151056090 ADVANCED MOLECULAR BIOLOGY This course covers protein and nucleic acid structure, DNA metabolism, gene expression, gene regulation, genomics and bioinformatics. The course will emphasize readings from the current literature. |
| 151056650 | LAB TECHNIQUES | This course will focus on enriching students’ practical research skills and developing their ability in designing research and experiments to answer a specific biological question. They will get introduced to different techniques used in the field of molecular genetics including mutagenesis primer design and mutagenesis PCR, Bacterial transformation and selection for colonies expressing mutated plasmid, plasmid sequencing, RFLP and ARMS, Cell transfection and infection, RNA extraction, cDNA synthesis and Real time PCR , Protein isolation and western blots, | 3 | - | 3 |
- |
| 151056700 | IMMUNOGENETICS | 3 | - | 3 |
- |
|
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